Pyruvic Acid
Ordering Recommendation
An isolated pyruvic acid concentration has little clinical value. Preferred test is Lactate to Pyruvate Ratio, Whole Blood (2007935), which reports concentrations for lactate, pyruvate, and L:P ratio on the same specimen.
New York DOH Approval Status
Specimen Required
Patient should be fasting and at complete rest. Patient should avoid any exercise of the arm or hand before or during collection. Draw the specimen without the use of a tourniquet or within three minutes of applying the tourniquet, but before releasing the tourniquet.
Green (Sodium or Lithium Heparin).
If whole blood is collected in a syringe, transfer immediately to green (sodium or lithium heparin) tube before preparing specimen.
1) Immediately after blood is drawn, add exactly 1 mL whole blood to a chilled pyruvate collection tube containing 2 mL 8 percent (w/v) perchloric acid (ARUP supply #16567) available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
2) Mix well for 30 seconds then place in an ice bath for 10 minutes.
3) Centrifuge for 10 minutes at 1500 x g.
4) Decant 2 mL supernatant to an ARUP Standard Transport Tube and freeze. (Min: 1 mL)
Frozen.
Ambient: Unacceptable; Refrigerated: 2 days; Frozen: 4 weeks
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
0.030-0.107 mmol/L (venous blood)
Interpretive Data
Standard
Note
If less than 1 mL of blood is added to collection tube, pH of the supernatant will be too low for testing.
Hotline History
CPT Codes
84210
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0080310 | Pyruvic Acid | 14121-8 |
Aliases
- Pyruvate
- Pyruvic Acid